In controlled analgesic clinical trials, oral doses greater than 400 mg were no more effective than a 400 mg dose.The lowest effective dose for the shortest duration consistent with individual treatment goals should be used.IV (Caldolor): 400 to 800 mg IV every 6 hours as needed Use: For the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis Usual Adult Dose for PainĢ00 to 400 mg orally every 4 to 6 hours as needed Use: For the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis Usual Adult Dose for Rheumatoid Arthritis Individual patients may show a better response to 3200 mg/day compared with 2400 mg/day, although in well-controlled clinical trials, use of 3200 mg/day did not show a better mean response in terms of efficacy.In chronic conditions, a therapeutic response may be seen in a few days to a week but most often is observed by 2 weeks after a satisfactory response has been achieved, review and adjust dose to achieve the lowest dose that yields acceptable control.Patients with rheumatoid arthritis generally require higher doses than those with osteoarthritis.Maximum dose: 3200 mg/day (prescription strength) Individualize dose adjust dose up or down depending on severity of symptoms.Rheumatoid Arthritis and Osteoarthritis (including flare-ups of chronic disease):ġ200 to 3200 mg orally per day in divided doses 3 or 4 times a day Maximum dose: 1200 mg/day (over the counter) Initial dose: 200 mg orally every 4 to 6 hours may increase to 400 mg orally every 4 to 6 hours as needed
Use: For the relief of signs and symptoms of primary dysmenorrhea Usual Adult Dose for Osteoarthritis
Treatment should begin at the earliest onset of pain.Maximum dose: 3200 mg/day (prescription strength) 1200 mg/day (over-the-counter)
200 to 400 mg orally every 4 hours as needed
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